Best Medical Billing Software for Practice Revenue Cycle Streamlining

Top 8 Medical Billing Software to Simplify Your Practice in 2025

Published On:
February 23, 2024
Updated On:
April 28, 2025

Did you know that the US healthcare system faces a staggering loss of up to $5 million per week due to errors in medical billing

That’s a hefty price to pay for something as critical as billing, which is why choosing the right medical billing software for your practice is more important than ever. 

After extensive research and feedback from practices, we’ve rounded up the top 8 tools that stand out for their ability to streamline billing processes, reduce errors, and save you time. 

Keep reading to find the best fit for your practice and start optimizing your billing workflow today!

List of 8 Medical Billing Software 

We’ve compiled a list of the top medical billing software options after extensive research through forums and firsthand feedback from practices. These tools stand out based on real-world performance and user experience.

‍Here’s a sneak peak first:

Tools Best For Pricing
Noterro Billing, insurance, practitioner management Starts at $30/month (14-day free trial)
AdvancedMD Claims management Custom pricing
EZClaim Partnering with EHR systems Starts at $169/month/single user
PracticeSuite Unified, synchronized workflow Custom pricing
eClinicalWorks Billing, financial reporting Starts from $599/month/provider
DrChrono Flexible billing, mobile access Custom pricing
CareCloud Revenue cycle management Custom pricing
CollaborateMD Billing & electronic claim submission Starts at $255/month

1.  Noterro - Best for billing and insurance, practitioner management

Noterro

Noterro offers comprehensive medical invoice software designed to streamline payment processing and insurance billing. 

With robust features like payment processing, insurance claim management, and direct integrations with TELUS eClaims and Availity, it simplifies the entire billing workflow. 

This software for billing and coding helps manage claims, track payments, and generate invoices efficiently, making it an ideal choice for practices that need to handle both private pay and insurance billing seamlessly. 

Additionally, its features for membership management, AI note-taker, and many more make it a versatile and reliable tool for practices of all sizes.

Features & Pros:

  • Automated reminders to help reduce missed appointments.
  • Add primary, secondary, and tertiary insurance providers to streamline claims. 
  • Connects seamlessly with Square, QuickBooks, and Xero for payment and financial management.
  • Smooth payment processing with built-in invoicing.
  • Account for and manage discounts and coupons while billing.
  • Manage your practice on the go with full mobile functionality.
  • Secure patient records ensuring data privacy.
  • Intelligent tag suggestions to streamline patient charting.
  • Tailored forms to optimize patient intake and improve workflow.

Cons:

  • Limited third-party integrations beyond the included options.
  • New users may need some time to get used to the interface.

Pricing: Starts at $30/month with a 14-day free trial.

2. AdvancedMD - Best for claims management

AdvancedMD

AdvancedMD offers a robust medical billing solution that simplifies and automates billing tasks, making it easier for healthcare practices to manage claims, payments, and patient data. 

It offers features like real-time claim tracking, denial management, and reporting. With its ability to integrate with electronic health records (EHR) systems, it provides a comprehensive solution for practices of all sizes.

Features and Pros:

  • Real-time claim tracking and automated claim submission.

  • Integrated with EHR systems for seamless workflow.

  • Denial management and customizable reporting.

  • User-friendly interface for easy navigation.

  • Cloud-based for access anywhere, anytime.

Cons:

  • Pricing may be on the higher side for smaller practices.

  • Customer support response times could be improved.

Pricing: Custom pricing.

Features and Pros:

  • Real-time claim tracking and automated claim submission.

  • Integrated with EHR systems for seamless workflow.

  • Denial management and customizable reporting.

  • User-friendly interface for easy navigation.

  • Cloud-based for access anywhere, anytime.

Cons:

  • Pricing may be on the higher side for smaller practices.

  • Customer support response times could be improved.

Pricing: Custom pricing.

3. EZClaim - Best for partnering with EHR systems

EZClaim

EZClaim is a cost-effective medical billing software designed for small to mid-sized practices. 

It simplifies billing processes with features like claim management, patient billing, and reporting, helping practices save time and reduce errors. 

With its user-friendly interface and ability to integrate with various clearinghouses, EZClaim is a reliable tool for practices looking to manage their billing more efficiently. It’s particularly useful for practices that need a straightforward, affordable solution without sacrificing functionality.

Features and Pros:

  • Claim management and submission to multiple clearinghouses.

  • Simple patient billing and payment tracking.

  • Customizable billing statements and reports.

  • Easy-to-use, no complex setup required.

  • Multi-user support for growing practices.

Cons:

  • Limited features for larger practices with complex billing needs.

  • Some users report occasional software bugs.

Pricing: Starts from $169/month/single user

4. PracticeSuite - Best for unified, synchornised workflow

PracticeSuite

PracticeSuite is a medical billing software that stands out for its high level of customization. Ideal for practices with unique billing workflows, it allows users to tailor the software to their specific needs. 

From claim submission to patient statements and collection tracking, PracticeSuite provides all the necessary tools to streamline billing. Its flexibility makes it especially useful for practices that require a more personalized approach to billing.

Features and Pros:

  • Customizable billing workflows to suit practice needs.

  • Integrated with EHR and patient scheduling systems.

  • Automated claim submission and denial management.

  • Real-time reports for better financial management.

  • Multi-location support for large practices.

Cons:

  • Can be complex to set up and configure initially.

  • Limited customer support options compared to competitors.

Pricing: Custom pricing.

5. eClinicalWorks - Best for billing and financial reporting

eClinicalWorks

eClinicalWorks is a widely-used medical billing software that integrates seamlessly with EHR, making it an all-in-one solution for practices seeking efficiency. It handles everything from scheduling and charting to billing and insurance claims. 

It's particularly favored by larger practices and healthcare networks due to its scalability and comprehensive functionality.

Features and Pros:

  • Complete integration with EHR and practice management.

  • Automated claims processing, denial resolution, and claim scrubbing.

  • Real-time payment posting and tracking.
  • Customizable billing statements and reports.
  • Telemedicine support for virtual visits.

Cons:

  • Can be overwhelming for smaller practices due to its complexity.

  • Customer service can be slow during peak times.

Pricing: Starts from $599/month/provider.

6. DrChrono - Best for flexible billing and mobile access

DrChrono

DrChrono offers a medical billing solution that’s perfect for practices seeking flexibility and mobility. It provides an integrated EHR, practice management, and billing solution, all accessible from any device, including smartphones and tablets. 

The software’s mobile functionality is a standout, allowing providers to manage billing while on the go. DrChrono offers a comprehensive solution with a focus on accessibility and ease of use.

Features and Pros:

  • Integrated billing, EHR, and practice management.

  • Customizable billing statements and payment reminders.
  • Offers claim submission, payment posting, and revenue cycle management.

  • Real-time claim tracking and payment posting.

  • Scalable for practices of various sizes.

Cons:

  • Some users report a steep learning curve.

  • Limited reporting features compared to other tools.

Pricing: Custom pricing

7. CareCloud - Best for revenue cycle management

CareCloud

CareCloud offers a cloud-based medical billing solution that focuses on modernizing billing processes for healthcare providers. 

With features like automatic claims processing, patient billing, and integrated reporting, CareCloud helps practices improve revenue cycle management and reduce administrative workload. 

Its user-friendly interface and cloud-based infrastructure make it easy for practices to access data from anywhere, while also offering integration with EHR and other healthcare management tools.

Features and Pros:

  • Automated claims submission and tracking.

  • Integrated with EHR for a seamless workflow.

  • Customizable patient billing statements.

  • Real-time reports and analytics for financial management.

  • Cloud-based for remote access.

Cons:

  • Some advanced features may be costly for smaller practices.

  • Limited customer support options during non-business hours.

Pricing: Custom pricing.

8. CollaborateMD - Best for billing and electronic claim submission

CollaborateMD

CollaborateMD is designed to simplify billing for small to mid-sized practices. Its streamlined features help practices manage patient billing, claims, and payments with ease. 

CollaborateMD offers real-time claim status tracking, automated patient billing, and denial management, making it a strong option for practices seeking efficiency. 

Its multi-user access is ideal for growing practices, allowing staff members to collaborate seamlessly on billing tasks.

Features and Pros:

  • Real-time claim status tracking and automated submissions.

  • Customizable billing reports and statements.

  • Multi-user access for growing practices.

  • Automated patient billing and payment reminders.

  • Cloud-based, allowing access from any device.

Cons:

  • Limited reporting features compared to competitors.

  • Some users report a learning curve with the interface.

Pricing: Starts at $255/month.

Now that you know the tools you can choose from, let’s also check out the tips to choose the best one.

Bonus read: 16 Practice Management Software Features Chiropractors Shouldn’t Ignore

What to Look for in the Best Medical Billing Software

Choosing the right medical billing solution doesn’t have to be overwhelming. I’d recommend that you keep these key factors in mind:

  • Features: Look for essential tools like claim submission, payment tracking, denial updates, and integration with your other systems.

  • Ease of Use: Find software that’s user-friendly with an intuitive interface and helpful training materials.

  • Scalability: Ensure the software can grow with your practice and handle more claims and users as needed.

  • Customer Support: Reliable, friendly support is a must—make sure help is just a call away when you need it.

  • Cost: Review pricing carefully, including upfront costs, fees, and potential savings. Consider the return on investment.

  • Integration: Check if the software integrates smoothly with your existing systems like EHR or practice management tools.

And here’s a tip:

Involve your team—practitioners, admins, and billing staff—in the decision-making process. Their input can help you find the best fit for your practice!



Next, let’s have a quick look at why having a reliable medical billing solution makes sense for your practice.

Why You Need Reliable Medical Billing Software for Healthcare Practices

Unreliable billing can cause major headaches for the practitioners. Investing in a reliable medical billing platform can transform your clinic’s operations, reducing errors and saving valuable time. 

Here are the reasons why:

The Importance of medical billing software

Helpful read: 9 Chiropractic Billing & Coding Red Flags (And How to Avoid Them)

Which Medical Billing Software is the Best?

After researching and analyzing the options, a few medical billing solution tools truly stood out. Each of them offers unique features that cater to different practice needs.

For those seeking robust insurance billing with advanced AI capabilities, Noterro is a top choice. However, if the focus is on comprehensive revenue cycle management, CareCloud provides an excellent all-in-one solution.

Ultimately, the right choice depends on specific practice requirements—take the time to explore these tools and find the one that fits your needs best!

FAQs

What are the different types of medical billing software?

There are four main types - Standalone Billing Software which focuses on billing and requires integration with other systems, Integrated Practice Management Software which combines billing with scheduling, patient registration, and EHR, Cloud-Based Medical Billing Software which can be accessed online, offering flexibility and automatic updatesm and EHR-Integrated Billing Software which syncs billing with EHR systems to improve accuracy and efficiency.

How secure is the data stored in medical billing software?

Noterro ensures data security by being fully compliant with PIPEDA and HIPAA standards. With robust encryption and secure cloud infrastructure, your patient and billing data is protected and handled with the highest level of confidentiality.

Software Key Features Ease of Use Scalability Customer Support
Noterro Practice management software, billing, scheduling, charting 5/5 5/5 5/5
AdvancedMD Specialty-specific features, telemedicine platform 4/5 5/5 4/5
Epic Systems Integrated EHR and billing, customization options available 4/5 4/5 4/5
AthenaCollector Denial management, revenue reporting 5/5 5/5 5/5
eClinicalWorks Insurance eligibility checks, EHR integration 4/5 4/5 4/5
NextGen Healthcare Claims management, revenue reporting 5/5 4/5 5/5
DrChrono EHR-integrated billing, mobile app 4/5 5/5 4/5
CareCloud Practice management, analytics 4/5 4/5 4/5
NueMD Patient portal, appointment scheduling 5/5 5/5 5/5
CollaborateMD Claims scrubbing, ERA processing 4/5 4/5 4/5

Table of Contents

Did you know that the US healthcare system faces a staggering loss of up to $5 million per week due to errors in medical billing

That’s a hefty price to pay for something as critical as billing, which is why choosing the right medical billing software for your practice is more important than ever. 

After extensive research and feedback from practices, we’ve rounded up the top 8 tools that stand out for their ability to streamline billing processes, reduce errors, and save you time. 

Keep reading to find the best fit for your practice and start optimizing your billing workflow today!

List of 8 Medical Billing Software 

We’ve compiled a list of the top medical billing software options after extensive research through forums and firsthand feedback from practices. These tools stand out based on real-world performance and user experience.

‍Here’s a sneak peak first:

Tools Best For Pricing
Noterro Billing, insurance, practitioner management Starts at $30/month (14-day free trial)
AdvancedMD Claims management Custom pricing
EZClaim Partnering with EHR systems Starts at $169/month/single user
PracticeSuite Unified, synchronized workflow Custom pricing
eClinicalWorks Billing, financial reporting Starts from $599/month/provider
DrChrono Flexible billing, mobile access Custom pricing
CareCloud Revenue cycle management Custom pricing
CollaborateMD Billing & electronic claim submission Starts at $255/month

1.  Noterro - Best for billing and insurance, practitioner management

Noterro

Noterro offers comprehensive medical invoice software designed to streamline payment processing and insurance billing. 

With robust features like payment processing, insurance claim management, and direct integrations with TELUS eClaims and Availity, it simplifies the entire billing workflow. 

This software for billing and coding helps manage claims, track payments, and generate invoices efficiently, making it an ideal choice for practices that need to handle both private pay and insurance billing seamlessly. 

Additionally, its features for membership management, AI note-taker, and many more make it a versatile and reliable tool for practices of all sizes.

Features & Pros:

  • Automated reminders to help reduce missed appointments.
  • Add primary, secondary, and tertiary insurance providers to streamline claims. 
  • Connects seamlessly with Square, QuickBooks, and Xero for payment and financial management.
  • Smooth payment processing with built-in invoicing.
  • Account for and manage discounts and coupons while billing.
  • Manage your practice on the go with full mobile functionality.
  • Secure patient records ensuring data privacy.
  • Intelligent tag suggestions to streamline patient charting.
  • Tailored forms to optimize patient intake and improve workflow.

Cons:

  • Limited third-party integrations beyond the included options.
  • New users may need some time to get used to the interface.

Pricing: Starts at $30/month with a 14-day free trial.

2. AdvancedMD - Best for claims management

AdvancedMD

AdvancedMD offers a robust medical billing solution that simplifies and automates billing tasks, making it easier for healthcare practices to manage claims, payments, and patient data. 

It offers features like real-time claim tracking, denial management, and reporting. With its ability to integrate with electronic health records (EHR) systems, it provides a comprehensive solution for practices of all sizes.

Features and Pros:

  • Real-time claim tracking and automated claim submission.

  • Integrated with EHR systems for seamless workflow.

  • Denial management and customizable reporting.

  • User-friendly interface for easy navigation.

  • Cloud-based for access anywhere, anytime.

Cons:

  • Pricing may be on the higher side for smaller practices.

  • Customer support response times could be improved.

Pricing: Custom pricing.

Features and Pros:

  • Real-time claim tracking and automated claim submission.

  • Integrated with EHR systems for seamless workflow.

  • Denial management and customizable reporting.

  • User-friendly interface for easy navigation.

  • Cloud-based for access anywhere, anytime.

Cons:

  • Pricing may be on the higher side for smaller practices.

  • Customer support response times could be improved.

Pricing: Custom pricing.

3. EZClaim - Best for partnering with EHR systems

EZClaim

EZClaim is a cost-effective medical billing software designed for small to mid-sized practices. 

It simplifies billing processes with features like claim management, patient billing, and reporting, helping practices save time and reduce errors. 

With its user-friendly interface and ability to integrate with various clearinghouses, EZClaim is a reliable tool for practices looking to manage their billing more efficiently. It’s particularly useful for practices that need a straightforward, affordable solution without sacrificing functionality.

Features and Pros:

  • Claim management and submission to multiple clearinghouses.

  • Simple patient billing and payment tracking.

  • Customizable billing statements and reports.

  • Easy-to-use, no complex setup required.

  • Multi-user support for growing practices.

Cons:

  • Limited features for larger practices with complex billing needs.

  • Some users report occasional software bugs.

Pricing: Starts from $169/month/single user

4. PracticeSuite - Best for unified, synchornised workflow

PracticeSuite

PracticeSuite is a medical billing software that stands out for its high level of customization. Ideal for practices with unique billing workflows, it allows users to tailor the software to their specific needs. 

From claim submission to patient statements and collection tracking, PracticeSuite provides all the necessary tools to streamline billing. Its flexibility makes it especially useful for practices that require a more personalized approach to billing.

Features and Pros:

  • Customizable billing workflows to suit practice needs.

  • Integrated with EHR and patient scheduling systems.

  • Automated claim submission and denial management.

  • Real-time reports for better financial management.

  • Multi-location support for large practices.

Cons:

  • Can be complex to set up and configure initially.

  • Limited customer support options compared to competitors.

Pricing: Custom pricing.

5. eClinicalWorks - Best for billing and financial reporting

eClinicalWorks

eClinicalWorks is a widely-used medical billing software that integrates seamlessly with EHR, making it an all-in-one solution for practices seeking efficiency. It handles everything from scheduling and charting to billing and insurance claims. 

It's particularly favored by larger practices and healthcare networks due to its scalability and comprehensive functionality.

Features and Pros:

  • Complete integration with EHR and practice management.

  • Automated claims processing, denial resolution, and claim scrubbing.

  • Real-time payment posting and tracking.
  • Customizable billing statements and reports.
  • Telemedicine support for virtual visits.

Cons:

  • Can be overwhelming for smaller practices due to its complexity.

  • Customer service can be slow during peak times.

Pricing: Starts from $599/month/provider.

6. DrChrono - Best for flexible billing and mobile access

DrChrono

DrChrono offers a medical billing solution that’s perfect for practices seeking flexibility and mobility. It provides an integrated EHR, practice management, and billing solution, all accessible from any device, including smartphones and tablets. 

The software’s mobile functionality is a standout, allowing providers to manage billing while on the go. DrChrono offers a comprehensive solution with a focus on accessibility and ease of use.

Features and Pros:

  • Integrated billing, EHR, and practice management.

  • Customizable billing statements and payment reminders.
  • Offers claim submission, payment posting, and revenue cycle management.

  • Real-time claim tracking and payment posting.

  • Scalable for practices of various sizes.

Cons:

  • Some users report a steep learning curve.

  • Limited reporting features compared to other tools.

Pricing: Custom pricing

7. CareCloud - Best for revenue cycle management

CareCloud

CareCloud offers a cloud-based medical billing solution that focuses on modernizing billing processes for healthcare providers. 

With features like automatic claims processing, patient billing, and integrated reporting, CareCloud helps practices improve revenue cycle management and reduce administrative workload. 

Its user-friendly interface and cloud-based infrastructure make it easy for practices to access data from anywhere, while also offering integration with EHR and other healthcare management tools.

Features and Pros:

  • Automated claims submission and tracking.

  • Integrated with EHR for a seamless workflow.

  • Customizable patient billing statements.

  • Real-time reports and analytics for financial management.

  • Cloud-based for remote access.

Cons:

  • Some advanced features may be costly for smaller practices.

  • Limited customer support options during non-business hours.

Pricing: Custom pricing.

8. CollaborateMD - Best for billing and electronic claim submission

CollaborateMD

CollaborateMD is designed to simplify billing for small to mid-sized practices. Its streamlined features help practices manage patient billing, claims, and payments with ease. 

CollaborateMD offers real-time claim status tracking, automated patient billing, and denial management, making it a strong option for practices seeking efficiency. 

Its multi-user access is ideal for growing practices, allowing staff members to collaborate seamlessly on billing tasks.

Features and Pros:

  • Real-time claim status tracking and automated submissions.

  • Customizable billing reports and statements.

  • Multi-user access for growing practices.

  • Automated patient billing and payment reminders.

  • Cloud-based, allowing access from any device.

Cons:

  • Limited reporting features compared to competitors.

  • Some users report a learning curve with the interface.

Pricing: Starts at $255/month.

Now that you know the tools you can choose from, let’s also check out the tips to choose the best one.

Bonus read: 16 Practice Management Software Features Chiropractors Shouldn’t Ignore

What to Look for in the Best Medical Billing Software

Choosing the right medical billing solution doesn’t have to be overwhelming. I’d recommend that you keep these key factors in mind:

  • Features: Look for essential tools like claim submission, payment tracking, denial updates, and integration with your other systems.

  • Ease of Use: Find software that’s user-friendly with an intuitive interface and helpful training materials.

  • Scalability: Ensure the software can grow with your practice and handle more claims and users as needed.

  • Customer Support: Reliable, friendly support is a must—make sure help is just a call away when you need it.

  • Cost: Review pricing carefully, including upfront costs, fees, and potential savings. Consider the return on investment.

  • Integration: Check if the software integrates smoothly with your existing systems like EHR or practice management tools.

And here’s a tip:

Involve your team—practitioners, admins, and billing staff—in the decision-making process. Their input can help you find the best fit for your practice!



Next, let’s have a quick look at why having a reliable medical billing solution makes sense for your practice.

Why You Need Reliable Medical Billing Software for Healthcare Practices

Unreliable billing can cause major headaches for the practitioners. Investing in a reliable medical billing platform can transform your clinic’s operations, reducing errors and saving valuable time. 

Here are the reasons why:

The Importance of medical billing software

Helpful read: 9 Chiropractic Billing & Coding Red Flags (And How to Avoid Them)

Which Medical Billing Software is the Best?

After researching and analyzing the options, a few medical billing solution tools truly stood out. Each of them offers unique features that cater to different practice needs.

For those seeking robust insurance billing with advanced AI capabilities, Noterro is a top choice. However, if the focus is on comprehensive revenue cycle management, CareCloud provides an excellent all-in-one solution.

Ultimately, the right choice depends on specific practice requirements—take the time to explore these tools and find the one that fits your needs best!

FAQs

What are the different types of medical billing software?

There are four main types - Standalone Billing Software which focuses on billing and requires integration with other systems, Integrated Practice Management Software which combines billing with scheduling, patient registration, and EHR, Cloud-Based Medical Billing Software which can be accessed online, offering flexibility and automatic updatesm and EHR-Integrated Billing Software which syncs billing with EHR systems to improve accuracy and efficiency.

How secure is the data stored in medical billing software?

Noterro ensures data security by being fully compliant with PIPEDA and HIPAA standards. With robust encryption and secure cloud infrastructure, your patient and billing data is protected and handled with the highest level of confidentiality.

Software Key Features Ease of Use Scalability Customer Support
Noterro Practice management software, billing, scheduling, charting 5/5 5/5 5/5
AdvancedMD Specialty-specific features, telemedicine platform 4/5 5/5 4/5
Epic Systems Integrated EHR and billing, customization options available 4/5 4/5 4/5
AthenaCollector Denial management, revenue reporting 5/5 5/5 5/5
eClinicalWorks Insurance eligibility checks, EHR integration 4/5 4/5 4/5
NextGen Healthcare Claims management, revenue reporting 5/5 4/5 5/5
DrChrono EHR-integrated billing, mobile app 4/5 5/5 4/5
CareCloud Practice management, analytics 4/5 4/5 4/5
NueMD Patient portal, appointment scheduling 5/5 5/5 5/5
CollaborateMD Claims scrubbing, ERA processing 4/5 4/5 4/5

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Get started with
Noterro today!

Try Noterro and discover that running your practice doesn’t need to feel overwhelming
Invoice

Get started with
Noterro today!

Try Noterro and discover that running your practice doesn’t need to feel overwhelming
calendar date picker
invoice